Flavor-Packed Santa Fe Chicken Skillet

The first time I made this Santa Fe Chicken Skillet, it was out of desperation on a weeknight when I had no energy, little time, and a fridge full of random ingredients. I threw together some chicken, canned veggies, and spices, and what came out of the oven surprised me—it was bold, hearty, cheesy, and soul-satisfying. That happy accident has since become my go-to “I need dinner fast” solution.

This easy sheet pan dinner is perfect for beginner cooks because it’s fast (ready in about 30 minutes), uses everyday pantry staples, and delivers impressive flavor with minimal effort. Plus, it’s a quick and healthy meal loaded with lean protein, fiber, and vegetables, making it a no-brainer for busy nights.

Flavor-Packed Santa Fe Chicken Skillet

Why This Recipe is Special

This Santa Fe-inspired chicken dish brings together classic Tex-Mex flavors—think smoky paprika, bright tomatoes, and melty cheese—with the convenience of a one-pan skillet. Unlike recipes that require marinating or complicated steps, this one uses canned vegetables and pre-shredded cheese to save time. It’s flexible, forgiving, and endlessly customizable. Whether you’re cooking for picky eaters or just learning your way around the kitchen, this dish sets you up for success.

Ingredients and Preparation

Chicken
The star of the dish, chicken breast provides lean protein and a neutral base for bold seasonings. Thinly slicing the breasts into cutlets ensures they cook quickly and evenly. You can also use boneless chicken thighs for a juicier result.

Garlic Powder and Chili Powder
These pantry spices bring instant flavor. Garlic powder offers a subtle savory kick, while chili powder adds warmth without overwhelming heat.

Olive Oil
Used for sautéing, it helps brown the chicken and vegetables while adding richness. Avocado oil or any neutral cooking oil works just as well.

Onion
A sweet onion like Vidalia adds depth and natural sweetness. Yellow or red onions are great substitutes.

Canned Diced Tomatoes with Green Chilies (like Rotel)
These bring tanginess and a gentle heat. If you want a milder flavor, use plain diced tomatoes and add chopped green bell peppers or a mild green chili.

Black Beans and Corn
Staples of the Tex-Mex pantry, they provide creaminess, sweetness, fiber, and color. Canned versions make prep a breeze. You can also use frozen corn or cooked pinto beans.

Smoked Paprika
Adds a deep, smoky note that brings the whole dish together. If you don’t have it, regular paprika or a dash of cumin can work in a pinch.

Mexican Cheese Blend
This pre-shredded mix of cheeses melts beautifully and brings a gooey finish. Use cheddar or Monterey Jack if that’s what you have on hand.

Fresh Cilantro (Optional)
For a bright, fresh finish. If you’re not a fan, skip it or use green onions.

Step-by-Step Instructions

Step 1
Preheat your oven to 400°F and position the rack in the middle of the oven. Slice each chicken breast in half horizontally to create four thinner cutlets and season both sides generously with garlic powder, chili powder, salt, and pepper.

Step 2
Heat olive oil in a large, oven-safe skillet over medium-high heat. Once the oil is shimmering, add the chicken and sear for about 3–4 minutes per side until golden brown. Remove the chicken and set aside on a plate.

Step 3
In the same skillet, add chopped onion and sauté for about 5 minutes until soft and lightly browned. This step lifts any flavorful bits left behind by the chicken.

Step 4
Add the canned diced tomatoes, black beans, corn, and smoked paprika to the skillet. Stir everything together and let it simmer for 2–3 minutes to warm through. Use a wooden spoon to scrape up any remaining browned bits from the bottom of the pan.

Step 5
Return the chicken to the skillet, nestling it into the mixture. Spoon some of the veggie mixture on top of the chicken and sprinkle everything generously with the shredded cheese, focusing it over the chicken pieces.

Step 6
Transfer the skillet to the oven and bake for 5–7 minutes, or until the chicken is fully cooked (internal temperature of 165°F) and the cheese is melted and bubbly. For a golden cheese top, broil for an extra 1–2 minutes at the end—but keep a close eye to avoid burning.

Step 7
Remove from the oven, top with fresh cilantro if using, and serve immediately.

Beginner Tips and Notes

  • Chicken sticking to the pan? Don’t force it—wait another minute. Meat naturally releases when it’s properly seared.
  • Don’t have an oven-safe skillet? Simply transfer the mixture to a baking dish before adding cheese and baking.
  • No meat thermometer? Cut into the thickest part of the chicken—if juices run clear and it’s no longer pink inside, it’s done.
  • Want it spicier? Add a chopped jalapeño or use hot Rotel instead of mild.

Serving Suggestions

This dish is hearty on its own, but it pairs beautifully with:

  • A side of cilantro-lime rice or plain brown rice for extra fiber
  • Warm tortillas or tortilla chips for scooping
  • A crisp side salad like avocado corn salad or cabbage slaw for a fresh crunch
  • Sour cream, salsa, or guacamole as toppings

Storage Tips

Let leftovers cool, then store in an airtight container in the fridge for up to 3–4 days. Reheat in a skillet over low heat or microwave in 30-second bursts, covered. Due to the texture of beans and corn, freezing is not recommended.

Conclusion

This lemon herb chicken recipe—Santa Fe-style—is a surefire win for anyone seeking quick and healthy meals with bold flavor and minimal cleanup. Whether you’re new to cooking or just want an effortless dinner, this dish delivers on all fronts. Try it out, make it your own with a few swaps, and don’t forget to drop a comment with your tweaks or serving ideas—I’d love to hear how it goes!

FAQ About Santa Fe Chicken Skillet

1. Can I make this Santa Fe Chicken Skillet ahead of time?

Yes, you can prepare the entire dish up to 1 day in advance and reheat it in the oven or on the stovetop. However, for the best cheese texture, add the cheese just before reheating.

2. What can I use instead of canned Rotel tomatoes?

If you don’t have Rotel, use regular diced tomatoes and add a small can of green chilies or chopped fresh jalapeños for that signature flavor kick.

3. How do I know when the chicken is fully cooked?

The chicken is done when it reaches an internal temperature of 165°F. You can also cut into the thickest piece—if the juices run clear and it’s no longer pink, it’s ready.

4. Is this recipe spicy?

The dish has a mild to moderate heat level depending on the type of Rotel used. For a milder version, choose mild Rotel or regular diced tomatoes. Add jalapeños for more heat.

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Flavor-Packed Santa Fe Chicken Skillet

Flavor-Packed Santa Fe Chicken Skillet


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  • Author: Ashely
  • Total Time: 30 minutes
  • Yield: 4 servings 1x
  • Diet: Low Fat

Description

A quick and healthy Santa Fe Chicken Skillet recipe packed with bold Tex-Mex flavors, perfect for beginner cooks and ready in just 30 minutes.


Ingredients

Scale
  • 2 large chicken breasts
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon chili powder
  • Salt and pepper to taste
  • 2 tablespoons olive oil
  • 1/2 medium onion, chopped
  • 1 (10-ounce) can diced tomatoes with green chilies (e.g., Rotel), drained
  • 1 (14-ounce) can black beans, drained and rinsed
  • 1 (12-ounce) can corn, drained
  • 1/2 teaspoon smoked paprika
  • 1 cup Mexican cheese blend
  • Fresh cilantro, chopped (optional)

Instructions

  1. Preheat the oven to 400°F and move the rack to the middle position. Slice each chicken breast in half horizontally to create four cutlets and season both sides with garlic powder, chili powder, salt, and pepper.
  2. Heat olive oil in a large oven-safe skillet over medium-high heat. Add the chicken and cook for 3–4 minutes per side until golden brown. Remove the chicken and set it aside.
  3. Add chopped onion to the skillet and sauté for about 5 minutes until softened and lightly browned. Stir in the diced tomatoes, black beans, corn, and smoked paprika.
  4. Simmer for 2–3 minutes to heat through and scrape up any browned bits from the pan.
  5. Return the chicken to the skillet and spoon some of the veggie mixture on top. Sprinkle the shredded cheese over everything.
  6. Transfer the skillet to the oven and bake for 5–7 minutes, or until the chicken is cooked through (165°F) and the cheese is melted. Broil for 1–2 minutes for a golden top, if desired.
  7. Garnish with chopped cilantro if using and serve immediately.

Notes

  • If chicken sticks to the pan, let it sear longer—it will release naturally when ready.
  • Use a baking dish if your skillet isn’t oven-safe.
  • Rotel is mildly spicy; use regular diced tomatoes for a milder version.
  • Check doneness with a meat thermometer or by cutting into the thickest piece.
  • Prep Time: 10 minutes
  • Cook Time: 20 minutes
  • Category: Main Course
  • Method: Skillet + Oven Baked
  • Cuisine: Tex-Mex

Nutrition

  • Serving Size: 1 cutlet with veggie topping
  • Calories: 420
  • Sugar: 5g
  • Sodium: 700mg
  • Fat: 18g
  • Saturated Fat: 7g
  • Unsaturated Fat: 9g
  • Trans Fat: 0g
  • Carbohydrates: 28g
  • Fiber: 6g
  • Protein: 38g
  • Cholesterol: 100mg

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